| 2022-12-08 12:20:2608/12/2022 | Fickenvicken  | 2 - 2 |  Defensor FC | 12:20:2612:20 |
| 2022-12-04 12:20:0004/12/2022 | Santiago Norte  | 0 - 2 | Defensor FC | 12:20:0012:20 |
| 2022-11-27 09:00:0027/11/2022 | Senegal  | 0 - 0 | Defensor FC | 09:00:0009:00 |
| 2022-11-20 09:00:0020/11/2022 | Defensor FC | 2 - 0 |  LIV | 09:00:0009:00 |
| 2022-11-13 09:00:0013/11/2022 | Cachaña Old Boys  | 5 - 2 | Defensor FC | 09:00:0009:00 |
| 2022-11-06 12:20:0006/11/2022 | Defensor FC | 1 - 3 | Senegal | 12:20:0012:20 |
| 2022-10-23 12:20:0523/10/2022 | Gambeta  | 2 - 1 | Defensor FC | 12:20:0512:20 |
| 2022-10-16 10:40:3816/10/2022 | Hermandad FC  | 5 - 2 | Defensor FC | 10:40:3810:40 |
| 2022-10-02 12:20:3102/10/2022 | Defensor FC | 1 - 7 |  Paris St Maipú | 12:20:3112:20 |
| 2022-08-28 12:50:0028/08/2022 | Defensor FC | 1 - 1 |  Santa Julia | 12:50:0012:50 |
| 2022-06-26 13:30:5926/06/2022 | Nottingham Miedo  | 3 - 3 | Defensor FC | 13:30:5913:30 |
| 2022-06-12 12:50:4712/06/2022 | Fickenvicken | 2 - 0 | Defensor FC | 12:50:4712:50 |
| 2022-05-29 12:50:5829/05/2022 | CSD 373  | 3 - 2 | Defensor FC | 12:50:5812:50 |
| 2022-05-22 12:50:0022/05/2022 | Nottingham Miedo | 5 - 2 | Defensor FC | 12:50:0012:50 |
| 2022-05-15 11:10:0015/05/2022 | Real Juventud  | 3 - 1 | Defensor FC | 11:10:0011:10 |
| 2022-05-08 12:20:0008/05/2022 | Santa Julia | 6 - 1 | Defensor FC | 12:20:0012:20 |
| 2022-04-10 14:00:4410/04/2022 | Fickenvicken | 1 - 2 | Defensor FC | 14:00:4414:00 |
| 2022-04-03 12:20:0003/04/2022 | Defensor FC | 2 - 2 |  Bocheros | 12:20:0012:20 |
| 2022-03-27 09:00:0027/03/2022 | Defensor FC | 2 - 4 |  LDP | 09:00:0009:00 |
| 2022-03-20 12:20:0020/03/2022 | Gambeta | 2 - 0 | Defensor FC | 12:20:0012:20 |
